Qualcomm’s CEO Cristiano Amon just told Fortune something that should make every smartphone maker sweat: the smartphone’s reign as your primary device is ending, and 2026 is the year AI agents go mainstream on entirely new form factors. He’s not speculating from a conference stage. He’s actively building the hardware to make it happen — with OpenAI, Meta, and what he cryptically calls “pretty much all” major AI companies.

This isn’t a vague roadmap slide. Qualcomm is already powering OpenAI’s first push into hardware, and Amon confirmed that multiple secret devices are in development with AI labs that haven’t announced hardware plans yet. The man who runs the company inside nearly every Android phone on Earth is now betting his next decade on killing the product that made him rich.

The “Ecosystem of You” Is Qualcomm’s Post-Smartphone Bet

Amon’s vision has a name: the “ecosystem of you.” It’s not a single device. It’s a mesh of wearables — glasses with outward-facing cameras that see what you see, earbuds that hear what you hear, and an AI agent that stitches it all together into a persistent, context-aware assistant that follows you everywhere.

Think about what that actually means. Your phone sits in your pocket as a connectivity hub, but you stop touching it. The AI agent handles your calendar, reads the room (literally), answers questions before you ask them, and operates across every device on your body simultaneously. The screen — the thing that has defined personal computing since the iPhone launched in 2007 — becomes optional.

Qualcomm is already shipping chips for this world. The company makes silicon for Meta’s Ray-Ban smart glasses, powers automotive AI systems, and has diversified so aggressively over Amon’s five years as CEO that smartphones now represent a shrinking share of its revenue. The “ecosystem of you” isn’t a pivot announcement. It’s a description of what Qualcomm has already been building.

OpenAI, Meta, and a List of Companies Amon Won’t Name

Here’s where it gets interesting. When asked which AI companies Qualcomm is building hardware with, Amon said “pretty much all of them” — then specifically confirmed OpenAI and Meta, while declining to name others. That silence is louder than the names he dropped.

OpenAI has been rumored to be developing its own hardware since 2024, when reports surfaced about a collaboration with former Apple designer Jony Ive. Qualcomm powering that device makes strategic sense — the company already builds the most advanced mobile AI chips on the planet, and OpenAI needs silicon that can run inference locally without burning through battery life.

Meta’s involvement is more obvious. The Ray-Ban Meta glasses are already the most successful smart glasses ever made, and Meta has been transparent about building AI into every pair. But the “others” Amon won’t name? That’s the real story. Google, Amazon, Apple, Anthropic, and xAI all have reasons to explore dedicated AI hardware. If even half of them are in talks with Qualcomm, the post-smartphone hardware race is already further along than anyone publicly acknowledges.

Why This Is Different From Every Other “Smartphone Killer” Prediction

We’ve heard “the smartphone is dying” before. Google Glass flopped. The Humane AI Pin was a disaster. The Rabbit R1 was a glorified app launcher. Every attempt to replace the phone has failed because the replacement couldn’t do what a phone does.

Amon’s argument is different, and it’s worth taking seriously for three reasons.

First, the AI models are finally good enough. GPT-5.5, Claude Opus 4, Gemini 3.1 Ultra — these aren’t chatbots anymore. They can reason across text, images, and audio simultaneously. An AI agent running on a pair of glasses can now actually understand what you’re looking at and respond intelligently. That wasn’t true even 18 months ago.

Second, the silicon caught up. Qualcomm’s Snapdragon X series can run large language models locally with enough efficiency to last a full day on a wearable battery. On-device inference means your AI agent doesn’t need a constant cloud connection — it works in airplane mode, in a subway, in a dead zone. That solves the latency and privacy problems that killed every previous attempt.

Third, the business model shifted. Humane and Rabbit tried to sell standalone devices that competed with your phone. Amon isn’t doing that. The “ecosystem of you” treats the phone as infrastructure — a modem in your pocket — while the interaction layer moves to glasses, earbuds, rings, and pins. You don’t replace the phone. You stop looking at it.

The Numbers Behind the Bet

Qualcomm’s transformation is already visible in its financials. Under Amon, the company has diversified from being 80% smartphone-dependent to generating significant revenue from automotive, IoT, and XR (extended reality) segments. The automotive business alone is now a multi-billion dollar run rate, and the company’s AI-related design wins have exploded.

But here’s the tension: smartphones still pay the bills. Qualcomm’s Snapdragon 8 Gen 5 is inside every major Android flagship launching this year — the Samsung Galaxy S26 series, the OnePlus 16, the Xiaomi 16 Ultra. If the smartphone really is dying, Qualcomm is the company with the most to lose and the most to gain. Amon is essentially telling investors: trust me, I’ll cannibalize my own cash cow before someone else does.

That takes either extraordinary vision or extraordinary desperation. Given that Qualcomm’s stock has outperformed the S&P 500 under Amon’s leadership, the market is betting on vision.

What This Means for You

If Amon is right, the device you’re reading this on is the last generation of “primary” smartphones. Not because phones disappear — they’ll still exist as connectivity hubs — but because the way you interact with technology fundamentally changes. Instead of pulling a glass slab out of your pocket 150 times a day, an AI agent on your glasses or earbuds handles most of what you currently use your phone for.

The timeline Amon is implying is aggressive: meaningful adoption by late 2027, mainstream by 2028. That aligns with Apple’s expected smart glasses launch, Google’s next-generation AR push, and Meta’s planned transition from Ray-Ban partnership to a fully Meta-designed wearable.

The verdict: Every previous “smartphone killer” failed because it was a worse phone. Qualcomm’s bet is that AI agents don’t need to be a better phone — they need to make the phone irrelevant. And the fact that OpenAI, Meta, and unnamed others are already building hardware around this thesis means we’re past the speculation phase. The post-smartphone era isn’t a prediction anymore. It’s a product roadmap with Qualcomm’s chips inside it.